Skip to Main Content

Charles Holmes

Dr. Charles B. Holmes is Distinguished Scholar and Program Director of the Center for Innovation in Global Health, Policy and Law Initiative O’Neill Institute for National and Global Health Law, and Professor of Medicine, Georgetown University Medical School. Dr. Holmes is a physician who has held senior global health leadership roles in government, academia, and non-governmental organizations. He served as Chief Medical Officer and Deputy U.S. Global AIDS Coordinator for the PEPFAR program in the Department of State during the Obama-Biden administration, where he led technical policy development and initiatives to improve the effectiveness, resource allocation and accountability of US government investments and was founding Director of the Office of Research and Science. In 2013 he become CEO of the Centre for Infectious Disease Research in Zambia (CIDRZ) where he spent four years leading a staff of over 1,000 improving the quality and reach of Zambia’s national healthcare system, including care for over 200,000 people living with HIV. Dr. Holmes has extensive diplomatic experience working with government health and finance officials and civil society in many countries, and is a life member of the Council on Foreign Relations.

In his current role at Georgetown he provides strategic support to governments, multi-lateral and private sector organizations for improved health systems responses to the HIV epidemic, and leads research to optimize health systems performance. He is a frequent advisor to the Bill and Melinda Gates Foundation and the World Health Organization (WHO) where he serves as Co-Chair of the WHO Global Working Group for HIV Service Quality. Dr. Holmes is widely published in the research and policy literature and collaborated with former Senate Majority Leaders, Bill Frist and Tom Daschle to write a 2018 report on Strategic Health Diplomacy for the Bipartisan Policy Center in Washington, DC. Dr. Holmes trained in internal medicine and infectious diseases at Massachusetts General Hospital and Harvard Medical School, and has served on the full time or adjunct faculty of Johns Hopkins School of Medicine since 2011, where he has been an attending physician on the Mann infectious disease consult service at Johns Hopkins Hospital. He continues to serve as an adjunct faculty at the Johns Hopkins School of Medicine and Bloomberg School of Public Health.