Journal of the American Medical Association (JAMA)  |  November 13, 2023

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In 2021, 46% ($260 billion) of all gross prescription drug spending in the US was on biologic products. Patents are government-granted monopolies that last 20 years; by obtaining multiple patents for different aspects of the same product, biologic manufacturers create “patent thickets” that can block or delay biosimilar competition to protect market share

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