O'Neill Institute  |  September 14, 2026

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Sustaining effective HIV treatment and prevention is challenged by the need to maintain consistent engagement in care over the long term and satisfy the diverse needs of communities affected by HIV. This requires overcoming barriers to engagement such as limited access to transportation and medical providers. As longer-acting options for HIV treatment and PrEP become available, addressing barriers to HIV treatment and prevention will require going beyond brick-and- mortar clinic settings. Mobile health clinics offer an opportunity to combine the promise of these modalities for greater flexibility with novel engagement methods. Given the competing time demands and personal priorities, HIV treatment and prevention are often not the primary drivers of engagement in healthcare. Mobile health clinics seeking to deliver HIV treatment and PrEP should serve as low-barrier entry points to address the needs of people living with or at risk for HIV by providing medical and social services that people most often seek. Clinics that deliver a wide range of services and build trust among communities most impacted by HIV are more likely to see engagement with HIV treatment and prevention services.

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Issues

HIV/AIDS

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