O'Neill Institute  |  September 8, 2025

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The high cost of prescription drugs harms health and exacerbates disparities. Leveraging their traditional public health powers, states have pursued and adopted various innovative approaches to lower prescription drug prices. But these efforts are often met with litigation challenges, which sometimes derail the policies or chill policy momentum.

To help demystify litigation challenges, the Center for Health Policy and the Law is launching a series of publications addressing the common arguments that are made in litigation challenging state prescription drug pricing policies. In this first installment of the series, we address arguments over the Dormant Commerce Clause, explain how the courts have dealt with those arguments, and lay out how policymakers and other stakeholders may craft sound policies that can withstand Dormant-Commerce-Clause-based arguments.

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October 14, 2025

Charles Holmes Maggie Little, Ph.D.; Heidi Weimer, J.D., MPH, LL.M; Dylan Green, MPH; Alicia Patterson, Ph.D.; Jonathan Healey; Sydney Luken; Janet Tatenda Bhila; Aleny Couto, MD; Shona Dalal, PhD; Will Fleisher, PhD; Jen Gennai; Rayid Ghani; Peter Godfrey-Faussett; Melissa Goldstein, JD; Kathy Hageman, PhD, MPH; Nina Hasen, PhD; Micheal Ighodaro; Thoko Kalua, MBBS, MSc; Jennifer Miller, PhD; Yogan Pillay, PhD; Anton Pozniak, MD; Miriam Rabkin, MD, MPH; David Ribes, PhD; Lisa Singh, PhD