The New England Journal of Medicine   |  September 20, 2024

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In this O’Neill Institute Briefing, we explain the different mpox clades in circulation and examine the evolving outbreak. We then explore the international response, including the availability, approval and need for mpox vaccines, WHO’s recommendations to Member States under the IHR, and the contents of WHO and Africa CDC’s joint continental response plan. Finally, we present our own legal and policy recommendations to bring the emergency under control, and to prevent future outbreaks of mpox.

Issues

Mpox